Prospective study of thyroid functions in multiple sclerosis patients treated with interferon beta in Alexandria University MS clinic

Abstract Background The incidence of thyroid dysfunction in multiple sclerosis (MS) patients on interferon (as a disease-modifying line) has been reported many studies performed already therapy. Our study adopted prospective follow-up the profile those newly starting beta therapy over 1 year trying to find correlation between start and occurrence this dysfunction. Objectives To evaluate MS before after beta. Methods A cohort 48 receiving through clinic were subjected assessment including serum TSH, free T3, T4 at treatment; they followed-up 6- 12-month intervals Results conclusion There was statistically significant increase serum-free T3 levels treated with year. work also showed decrease without statistical significance. TSH tendency towards significance .